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Smart fillings that repair teeth from within

NCT ID NCT07688343

Disease control Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 07, 2026 · Last updated Jul 10, 2026 · Updated 3 times

Summary

This study compares four types of tooth fillings for cavities on the sides of back teeth. Three of the fillings release minerals like calcium and phosphate, which may help repair the tooth and prevent further decay. The fourth is a standard bulk-fill filling used for comparison. Over two years, researchers will check how well each filling holds up and how healthy the surrounding tooth remains.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ion-releasing restorative systems (tooth fillings that release minerals like calcium and phosphate)
What this could lead to
If successful, these fillings could help repair cavities and prevent future decay, reducing the need for repeat dental work.
What could go wrong
This is a small, early-stage study with only 40 participants, so results may not apply to everyone. The fillings may not perform better than standard options.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jun 2025

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * at least 4 carious posterior teeth Exclusion Criteria: * pregnancy - not able to attend for regular follow-up -smokers or very bad oral hygiene

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental caries

Contacts and locations

Locations

  • Faculty of Dentistry, Mansoura University

    Al Mansurah, Dakahlia Governorate, 35516, Egypt

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