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Smart fillings that repair teeth from within

NCT ID NCT07688343

Ongoing Disease control Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 10, 2026 · Updated 3 times

Summary

This study compares four types of tooth fillings for cavities on the sides of back teeth. Three of the fillings release minerals like calcium and phosphate, which may help repair the tooth and prevent further decay. The fourth is a standard bulk-fill filling used for comparison. Over two years, researchers will check how well each filling holds up and how healthy the surrounding tooth remains.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ion-releasing restorative systems (tooth fillings that release minerals like calcium and phosphate)
What this could lead to
If successful, these fillings could help repair cavities and prevent future decay, reducing the need for repeat dental work.
What could go wrong
This is a small, early-stage study with only 40 participants, so results may not apply to everyone. The fillings may not perform better than standard options.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DENTAL CARIES

Contacts and locations

Locations

  • Faculty of Dentistry, Mansoura University

    Al Mansurah, Dakahlia Governorate, 35516, Egypt

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