Can a simple dye test spot kidney trouble in the ICU?

NCT ID NCT02050269

Completed Diagnosis Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a dye called iohexol can accurately measure kidney function in 100 ICU patients with unstable blood pressure. The goal was to see if this method could help detect acute kidney injury earlier than current tests. Researchers tracked how quickly the dye cleared from the blood and compared it to other kidney injury markers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Iohexol (a contrast dye)
What this could lead to: If successful, this could provide a more accurate way to measure kidney function in critically ill patients, helping doctors detect kidney injury earlier.
What could go wrong: This is a small feasibility study, not a treatment trial. The method may not be practical or accurate enough for routine ICU use, and iohexol carries a small risk of allergic reactions.

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Conditions

The condition(s) this trial relates to.

Shock

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE CIRCULATORY FAILURE

Contacts and locations

Locations

Hospital La SOURCE

Orléans, 45000, France
Service de Réanimation Polyvalente, CHRU de Tours

Tours, 37044, France
University Hospital Strasbourg

Strasbourg, 67000, France

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