Chemo shot straight into tumor could cut side effects

NCT ID NCT07495098

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage trial tests injecting the chemotherapy drug cisplatin directly into lung tumors using a thin tube with a camera. The goal is to see if this approach is safe and can kill more cancer cells while causing fewer side effects than standard IV chemo. The study will enroll 12 adults with stage IV non-small cell lung cancer.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
cisplatin
What this could lead to
If it works, this could point toward a less toxic way to deliver chemotherapy directly into lung tumors, potentially improving treatment outcomes with fewer side effects.
What could go wrong
This is a very early Phase 1 trial with only 12 participants, so safety and dosing are still being tested. It may not work as hoped, and there are risks from the procedure itself, such as bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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