New ultrasound wand could spot mouth cancer without a knife

NCT ID NCT06336941

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new, high-frequency ultrasound probe that goes inside the mouth to look at suspicious spots. The goal is to see if it can accurately measure how deep a mouth cancer goes, which might help doctors diagnose it without always needing a surgical biopsy. The study will include 400 people with oral squamous cell carcinoma who are already scheduled for surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ultra-high frequency ultrasound probe (70 MHz)

What this could lead to

If successful, this could provide a non-surgical way to help diagnose oral cancer and measure how deep it goes, potentially reducing the need for biopsies.

What could go wrong

This is an early exploratory study, not a treatment trial. The ultrasound may not be accurate enough to replace biopsy, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Mouth Neoplasms oral cavity squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Università di Pisa

    RECRUITING

    Pisa, 56126, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••