Can simulated High-Altitude breathing boost lung cancer treatment?
NCT ID NCT07618793
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests whether adding intermittent hypoxic training (IHT) – short sessions of breathing low-oxygen air – to standard chemo-immunotherapy can improve outcomes for people with stage II-IIIA lung squamous cell carcinoma. About 60 participants will receive either standard treatment alone or standard treatment plus IHT before surgery. The main goal is to see if the combination leads to a higher rate of complete tumor disappearance at the time of surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Intermittent hypoxic training (IHT) using a low-oxygen device
- What this could lead to
- If successful, this approach could boost the effectiveness of standard cancer therapy, leading to higher rates of tumor disappearance before surgery and potentially longer survival.
- What could go wrong
- This is an early phase 2 trial with only 60 participants, so results may not apply broadly. The added training may cause discomfort or side effects, and it is unclear if it will meaningfully improve outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Xuanwu Hospital, Capital Medical University
Beijing, Beijing Municipality, 100053, China
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