New study combines addiction treatment and IV antibiotics outside the hospital

NCT ID NCT04677114

Completed Disease control Sponsor: Laura Fanucchi Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether people with opioid use disorder and severe injection-related infections can be safely treated at home with antibiotics and buprenorphine (a medication for opioid use disorder). 71 participants were enrolled. The goal was to see if this integrated approach reduces illicit opioid use and helps patients complete their antibiotic treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: buprenorphine (Suboxone or Sublocade) and intravenous antibiotics
What this could lead to: If successful, this approach could offer a safe, effective way to treat both opioid use disorder and severe infections without requiring a hospital stay.
What could go wrong: This is a small Phase 2 trial with only 71 participants, so results may not apply to everyone. The treatment requires careful monitoring and may not work for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DRUG USE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Infections opiate dependence subacute bacterial endocarditis substance abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRUG USE OPIOID-USE DISORDER

Contacts and locations

Locations

University of Kentucky

Lexington, Kentucky, 40515, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.