New study combines addiction treatment and IV antibiotics outside the hospital
NCT ID NCT04677114
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether people with opioid use disorder and severe injection-related infections can be safely treated at home with antibiotics and buprenorphine (a medication for opioid use disorder). 71 participants were enrolled. The goal was to see if this integrated approach reduces illicit opioid use and helps patients complete their antibiotic treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
buprenorphine (Suboxone or Sublocade) and intravenous antibiotics
What this could lead to
If successful, this approach could offer a safe, effective way to treat both opioid use disorder and severe infections without requiring a hospital stay.
What could go wrong
This is a small Phase 2 trial with only 71 participants, so results may not apply to everyone. The treatment requires careful monitoring and may not work for all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Kentucky
Lexington, Kentucky, 40515, United States