New skin patch could replace flap surgery for leg injuries
NCT ID NCT00906672
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compared two ways to cover deep wounds on the lower leg, ankle, or foot: a synthetic skin patch called Integra versus traditional flap surgery (moving skin from another body part). 72 patients with traumatic skin loss were enrolled. The goal was to see which method leads to fewer complications and better scar appearance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Integra dermal substitute (a synthetic skin patch)
What this could lead to
If Integra works as well as flap surgery with fewer complications, it could offer a simpler, less invasive option for covering leg wounds.
What could go wrong
This is a small, completed Phase 3 trial with only 72 participants. The results may not apply to all wound types or patients, and Integra may still require additional surgeries.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Saint Roch Hospital
Nice, 06003, France
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University Hospital
Besançon, 25030, France
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University Hospital
Clermont-Ferrand, 53003, France
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University Hospital
Grenoble, 38043, France
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University Hospital
Montpellier, 34295, France
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University Hospital
Pointe à Pitre, 97159, France
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Universiy Hospital Bordeaux,
Bordeaux, France