New skin patch could replace flap surgery for leg injuries

NCT ID NCT00906672

Completed Disease control Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two ways to cover deep wounds on the lower leg, ankle, or foot: a synthetic skin patch called Integra versus traditional flap surgery (moving skin from another body part). 72 patients with traumatic skin loss were enrolled. The goal was to see which method leads to fewer complications and better scar appearance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Integra dermal substitute (a synthetic skin patch)
What this could lead to: If Integra works as well as flap surgery with fewer complications, it could offer a simpler, less invasive option for covering leg wounds.
What could go wrong: This is a small, completed Phase 3 trial with only 72 participants. The results may not apply to all wound types or patients, and Integra may still require additional surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ankle injury Foot Injuries Leg Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANKLE INJURIES FOOT INJURIES LEG INJURIES

Contacts and locations

Locations

Saint Roch Hospital

Nice, 06003, France
University Hospital

Besançon, 25030, France
University Hospital

Clermont-Ferrand, 53003, France
University Hospital

Grenoble, 38043, France
University Hospital

Montpellier, 34295, France
University Hospital

Pointe à Pitre, 97159, France
Universiy Hospital Bordeaux,

Bordeaux, France

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