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Could a Sugar-Clamping technique slash Post-Surgery infections?

NCT ID NCT01528189

Disease control Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

This trial tests whether keeping blood sugar tightly controlled during major abdominal surgery reduces the risk of surgical site infections. Researchers will give some patients a continuous insulin and dextrose infusion to maintain normal glucose levels, while others receive standard glucose management. The study includes adults undergoing elective liver, pancreatic, or colorectal surgery. The goal is to see if this 'clamp' technique lowers infection rates and improves recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Insulin and dextrose infusion to maintain normal blood sugar during surgery
What this could lead to
If it works, this approach could reduce surgical site infections after major abdominal surgery, shortening hospital stays and improving recovery.
What could go wrong
The trial is early and the technique is complex, requiring careful monitoring. It may not lower infection rates compared to standard glucose management, and tight glucose control carries a risk of low blood sugar.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

480 people

The number who actually took part.

Started

Oct 2018

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \> 18 years old * elective liver, pancreatic or colorectal surgery * ability to give informed consent Exclusion Criteria:

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Conditions

The condition(s) this trial relates to.

Infections Insulin Resistance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Surgical site infection after major surgery

Contacts and locations

Locations

  • Hospital Clinico Universidad de Chile

    Independencia, Santiago Metropolitan, 8380456, Chile

  • Royal Victoria Hospital

    Montreal, Quebec, H3A1A1, Canada

  • Royal Victoria Hospital, McGill University Health Centre

    Montreal, Quebec, H3A 1A1, Canada

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