Can a custom breathing workout help patients leave the ventilator faster?

NCT ID NCT07761468

ENROLLING_BY_INVITATION Disease control Sponsor: Hospital H+ Queretaro Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial tests whether a specific daily 'dose' of inspiratory muscle training can strengthen the breathing muscles of adults on mechanical ventilation in the ICU. Patients are assigned to one of three training intensities, calculated using a new formula called the Total Inspiratory Work Unit (UTIT), and adjusted daily based on their breathing strength. The goal is to see which dose best improves muscle strength and reduces the total time spent on the ventilator.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Inspiratory muscle training using a POWERbreathe K5 device, with daily dose calculated by the Total Inspiratory Work Unit (UTIT) formula.
What this could lead to: If successful, this could establish a standardized, optimal dose of breathing-muscle training for ICU patients, potentially shortening time on ventilators and speeding recovery.
What could go wrong: This is a small, early-phase trial (60 patients) testing three doses, so results may not apply broadly. Training may not improve outcomes for all patients, and there is a risk of muscle fatigue or discomfort.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MECHANICAL VENTILATION WEANING RESPIRATORY MUSCLE WEAKNESS VENTILATOR INDUCED DIAPHRAGM DYSFUNCTION

Contacts and locations

Locations

Hospital H+ Querétaro, Santiago de Querétaro, Querétaro

Querétaro City, Querétaro, 76000, Mexico

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