New pacemaker for the diaphragm aims to free patients from ventilators faster

NCT ID NCT07477054

First seen Jun 24, 2026 · Last updated Aug 07, 2026 · Updated 4 times

Summary

This study tests a device called AeroPace that electrically stimulates the nerve controlling the diaphragm, the main breathing muscle. It is for adults who have been on a mechanical ventilator for at least 4 days and are having trouble weaning off. The goal is to see if the device is safe and helps patients breathe on their own within 30 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
AeroPace System (device that electrically stimulates the phrenic nerve to contract the diaphragm)
What this could lead to
If successful, this device could help people on breathing machines wean off ventilation faster and reduce complications from diaphragm weakness.
What could go wrong
This is a post-approval study collecting real-world data, not a randomized trial, so results may not prove the device is better than standard care. Risks include device-related serious adverse events.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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