New pacemaker for the diaphragm aims to free patients from ventilators faster

NCT ID NCT07477054

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a device called AeroPace that electrically stimulates the nerve controlling the diaphragm, the main breathing muscle. It is for adults who have been on a mechanical ventilator for at least 4 days and are having trouble weaning off. The goal is to see if the device is safe and helps patients breathe on their own within 30 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AeroPace System (device that electrically stimulates the phrenic nerve to contract the diaphragm)

What this could lead to

If successful, this device could help people on breathing machines wean off ventilation faster and reduce complications from diaphragm weakness.

What could go wrong

This is a post-approval study collecting real-world data, not a randomized trial, so results may not prove the device is better than standard care. Risks include device-related serious adverse events.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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