Can a simple gas save marginal liver grafts?
NCT ID NCT01172691
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether giving inhaled nitric oxide during liver transplant surgery could reduce damage to the new liver and help it work better. Twenty-three patients receiving a liver transplant were randomly assigned to get either the gas or a placebo. The goal was to see if the gas could protect so-called 'marginal' livers (those at higher risk of injury) and speed up recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Inhaled nitric oxide (iNO)
- What this could lead to
- If it works, this could help transplanted livers function better and reduce injury, potentially improving survival for patients receiving marginal grafts.
- What could go wrong
- This is a small, early-phase trial with only 23 participants, so results may not apply broadly. The treatment is given only during surgery, and long-term benefits are uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Baylor Univsersity Medical Center
Dallas, Texas, 75246, United States
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