Can a simple gas save marginal liver grafts?

NCT ID NCT01172691

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving inhaled nitric oxide during liver transplant surgery could reduce damage to the new liver and help it work better. Twenty-three patients receiving a liver transplant were randomly assigned to get either the gas or a placebo. The goal was to see if the gas could protect so-called 'marginal' livers (those at higher risk of injury) and speed up recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Inhaled nitric oxide (iNO)

What this could lead to

If it works, this could help transplanted livers function better and reduce injury, potentially improving survival for patients receiving marginal grafts.

What could go wrong

This is a small, early-phase trial with only 23 participants, so results may not apply broadly. The treatment is given only during surgery, and long-term benefits are uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor Univsersity Medical Center

    Dallas, Texas, 75246, United States