New Non-Opioid pill shows promise in breaking opioid addiction cycle

NCT ID NCT06384157

Completed Disease control Sponsor: Indivior Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new drug called INDV-2000 in 300 adults with moderate to severe opioid use disorder who wanted to stop using opioids. Participants were randomly assigned to receive different doses of INDV-2000 or a placebo for 3 months. The main goal was to see if the drug could help people stay opioid-free without needing other opioid medications, and to find the best dose. The study is now complete, and results will show how safe and effective this non-opioid treatment might be.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID USE DISORDER

Contacts and locations

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Locations

Accel Research Sites - Lakeland

Lakeland, Florida, 33803, United States
Agile Clinical Research Trials

Atlanta, Georgia, 30328, United States
Alpine Research Organisation

Clinton, Utah, 84015, United States
Arch Clinical Trials

St Louis, Missouri, 63141, United States
Artemis Institute For Clinical Research - San Diego

San Diego, California, 92103, United States
Boeson Clinical Research

Provo, Utah, 84604, United States
Bold City Clinical Research

Jacksonville, Florida, 32224, United States
Boyett Health Services Inc

Hamilton, Alabama, 35570, United States
Clinical Research Center of Florida

Pompano Beach, Florida, 33060, United States
Dr Vando Medical Services

The Bronx, New York, 10464, United States
El Paso Clinical Trials

El Paso, Texas, 79902, United States
Elite Clinical Studies, LLC

Phoenix, Arizona, 85018, United States
Empire Clinical Research

Pomona, California, 91767, United States
HD Research

Houston, Texas, 77043, United States
IMA Clinical Research

Las Vegas, Nevada, 89102, United States
Imagine Research of Palm Beach County

Boynton Beach, Florida, 33435, United States
Insight Research Institute

Flint, Michigan, 48507, United States
Insite Clinical Research, LLC

DeSoto, Texas, 75115, United States
Maryland Treatment Centers

Baltimore, Maryland, 21229, United States
Midwest Clinical Research Center, LLC

Dayton, Ohio, 45417, United States
Monroe Biomedical Research

Monroe, North Carolina, 28112, United States
North County Clinical Research

Oceanside, California, 92054, United States
Oasis Clinical Research

Las Vegas, Nevada, 89121, United States
Pahl Pharmaceutical Professionals, LLC

Oklahoma City, Oklahoma, 73112, United States
Precise Research Centers

Flowood, Mississippi, 39232, United States
Prisma Health Addiction Medicine Center

Greenville, South Carolina, 29605, United States
Progressive Clinical Research Llc

Bountiful, Utah, 84010, United States
Quantum Clinical Trials

Miami Beach, Florida, 33140, United States
Richmond Behavioral Associates

Staten Island, New York, 10314, United States
SP Research PLLC Rivus Wellness and Research Insitute

Oklahoma City, Oklahoma, 73112, United States
Segal Trials Miami Lakes

Miami Lakes, Florida, 33016, United States
Unity Clinical Research

Oklahoma City, Oklahoma, 73118, United States
Vitalix Clinical

Worcester, Massachusetts, 01608, United States
Vitalix Kissimmee

Kissimmee, Florida, 34741, United States
West Clinical Research

Morehead City, North Carolina, 28557, United States