Could a Twice-Yearly shot help kids with rare high cholesterol?
NCT ID NCT06597006
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a drug called inclisiran in children aged 2 to 12 who have a rare genetic condition that causes extremely high cholesterol. The goal is to see if the drug safely lowers their bad cholesterol compared to a placebo. Participants will receive either inclisiran or placebo for one year, then all will receive inclisiran for a second year.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-••••
Locations
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Childrens National Hospital
RECRUITINGWashington D.C., District of Columbia, 20010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Novartis Investigative Site
RECRUITINGVienna, 1090, Austria
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Novartis Investigative Site
RECRUITINGBeijing, Beijing Municipality, 100013, China
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Novartis Investigative Site
RECRUITINGFrankfurt am Main, Hesse, 60590, Germany
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Novartis Investigative Site
RECRUITINGIoannina, 455 00, Greece
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Novartis Investigative Site
RECRUITINGThessaloniki, 546 42, Greece
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Novartis Investigative Site
RECRUITINGKota Bharu, Kelantan, 16150, Malaysia
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Novartis Investigative Site
RECRUITINGAmsterdam, North Holland, 1105 AZ, Netherlands
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Novartis Investigative Site
RECRUITINGBloemfontein, Free State, 9301, South Africa
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Novartis Investigative Site
RECRUITINGTaichung, 407219, Taiwan
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Novartis Investigative Site
RECRUITINGTaipei, 111045, Taiwan
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Novartis Investigative Site
RECRUITINGAdana, Saricam, 01330, Turkey (Türkiye)
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Novartis Investigative Site
RECRUITINGAnkara, Yenimahalle, 06500, Turkey (Türkiye)
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Novartis Investigative Site
RECRUITINGIzmir, 35100, Turkey (Türkiye)
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Novartis Investigative Site
RECRUITINGSouthampton, SO16 6YD, United Kingdom
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UC San Francisco Medical Center
RECRUITINGSan Francisco, California, 94143, United States
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UC San Francisco Medical Center
RECRUITINGSan Francisco, California, 94143, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
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Washington Univ School Of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact
Contact Email: •••••@•••••