New pill shows promise for Hard-to-Treat uterine cancer
NCT ID NCT07522697
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial is testing a daily pill called Inavolisib in about 48 people with advanced endometrial cancer that has a specific genetic change (PIK3CA mutation). The drug targets that mutation to try to shrink tumors or stop them from growing. Researchers will measure how many patients respond to treatment and how long it takes for the cancer to progress.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Inavolisib (a targeted cancer drug taken as a daily pill)
- What this could lead to
- If successful, this could provide a new treatment option for people with advanced endometrial cancer that has a specific genetic mutation (PIK3CA), potentially shrinking tumors or slowing disease progression.
- What could go wrong
- This is an early phase 2 trial with only 48 participants and no comparison group, so results may not be definitive. The drug may cause side effects or not work for everyone, and it is not yet known if it improves survival.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
National Cancer Institute of Napoli, Division of Medical Oncology - Uro-Gynecology Department
Naples, 80131, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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