New study aims to cut Life-Threatening side effects in child leukemia transplants

NCT ID NCT07297914

Not yet recruiting Disease control Sponsor: Bambino Gesù Hospital and Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This large international study looks for better ways to manage stem cell transplants in children and young adults with high-risk or relapsed acute lymphoblastic leukemia (ALL). The goal is to reduce serious complications and long-term side effects while keeping the transplant's power to fight cancer. About 1,000 participants will be enrolled to test new treatment strategies across multiple substudies.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia graft versus host disease Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) GRAFT-VERSUS-HOST DISEASE STEM CELL TRANSPLANT

Contacts and locations

Locations

Goethe-Universität

Frankfurt, Germany
HUS-Yhtymae (HUS Helsinki University Hospital)

Helsinki, Finland
IRCCS Ospedale Pediatrico Bambino Gesù

Roma, RM, 00165, Italy
Rigshopsitalet, University Hospital

Copenhagen, Denmark
Robert- Debré Academic Hospital

Paris, France
St'Anna Children Hospital

Vienna, Austria
University Hospital

Oslo, Norway
University Hospital Motol

Prague, Czechia
University of Medical Sciences

Poznan, Poland

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