Sickle cell patients may get better kidney checks thanks to new study

NCT ID NCT04380610

Completed Knowledge-focused Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study worked to improve how doctors estimate kidney function in people with sickle cell disease. Researchers measured actual kidney function in 120 patients and used that data to develop a new formula tailored to sickle cell. The goal is to replace current equations that were designed for the general population and may be less accurate for sickle cell patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to better monitoring of kidney health in sickle cell patients, helping doctors catch problems earlier.
What could go wrong: This is an observational study focused on improving measurements, not testing a new treatment. The new equation may not prove more accurate in all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

glomerular disorder kidney disorder sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLOMERULAR DISEASE RENAL DISEASE SICKLE CELL DISEASE

Contacts and locations

Locations

St Jude Childrens Research Hospital

Memphis, Tennessee, 38106, United States
University of Alabama at Birmingham

Birmingham, Alabama, 35223, United States
University of Illinois Chicage

Chicago, Illinois, 60612, United States
University of Tennessee Health Science Center

Memphis, Tennessee, 38163, United States

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