Sickle cell patients may get better kidney checks thanks to new study

NCT ID NCT04380610

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study worked to improve how doctors estimate kidney function in people with sickle cell disease. Researchers measured actual kidney function in 120 patients and used that data to develop a new formula tailored to sickle cell. The goal is to replace current equations that were designed for the general population and may be less accurate for sickle cell patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to better monitoring of kidney health in sickle cell patients, helping doctors catch problems earlier.

What could go wrong

This is an observational study focused on improving measurements, not testing a new treatment. The new equation may not prove more accurate in all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

glomerular disorder kidney disorder sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • St Jude Childrens Research Hospital

    Memphis, Tennessee, 38106, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35223, United States

  • University of Illinois Chicage

    Chicago, Illinois, 60612, United States

  • University of Tennessee Health Science Center

    Memphis, Tennessee, 38163, United States