New trial aims to spare young brains from radiation damage

NCT ID NCT07338526

Recruiting now Disease control Sponsor: Tata Memorial Centre Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a newer type of radiation called proton therapy (IMPT) can treat children's brain tumors just as well as standard X-ray therapy (IMRT) but with fewer long-term side effects. About 94 children aged 6 to 16 with low-grade brain tumors will be randomly assigned to receive either proton or X-ray radiation. Researchers will track their survival, thinking skills, hormone health, and hearing over five years to see which treatment is safer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Intensity-modulated proton therapy (IMPT)
What this could lead to: If successful, this could show that proton therapy reduces long-term brain damage, hormone problems, and hearing loss in children treated for brain tumors, potentially making it the new standard of care.
What could go wrong: This is a relatively small trial (94 children) and proton therapy is expensive and not widely available. The study is still recruiting, so results are years away, and it may not show a clear advantage over standard X-ray therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BRAIN TUMOR BENIGN are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

benign neoplasm of brain brain cancer low grade glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN TUMOR BENIGN BRAIN TUMOR, PEDIATRIC

Contacts and locations

Locations

Tata Memorial Hospital
RECRUITING

Mumbai, Maharashtra, 400012, India

More trials for these conditions

Other studies related to the condition(s) this trial covers.