New trial aims to spare young brains from radiation damage

NCT ID NCT07338526

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a newer type of radiation called proton therapy (IMPT) can treat children's brain tumors just as well as standard X-ray therapy (IMRT) but with fewer long-term side effects. About 94 children aged 6 to 16 with low-grade brain tumors will be randomly assigned to receive either proton or X-ray radiation. Researchers will track their survival, thinking skills, hormone health, and hearing over five years to see which treatment is safer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Intensity-modulated proton therapy (IMPT)

What this could lead to

If successful, this could show that proton therapy reduces long-term brain damage, hormone problems, and hearing loss in children treated for brain tumors, potentially making it the new standard of care.

What could go wrong

This is a relatively small trial (94 children) and proton therapy is expensive and not widely available. The study is still recruiting, so results are years away, and it may not show a clear advantage over standard X-ray therapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

benign neoplasm of brain brain cancer low grade glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tata Memorial Hospital

    RECRUITING

    Mumbai, Maharashtra, 400012, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••