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Massive study to track what happens when AML comes back

NCT ID NCT06459024

Recruiting now Knowledge-focused Sponsor: Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This observational study will follow 4,000 people whose acute myeloid leukemia has returned or not responded to treatment. Researchers will collect data from routine care to understand survival rates and treatment patterns over up to 4 years. No new drugs are being tested; the goal is to learn from real-world experiences.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could reveal which current treatments work best for relapsed/refractory AML, guiding future care decisions.
What could go wrong
This is an observational study, not a treatment trial, so it will not directly test new therapies. Results may be limited by real-world data variability.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE MYELOID LEUKEMIA REFRACTORY ACUTE MYELOID LEUKEMIA, IN RELAPSE

Contacts and locations

Locations

  • AO Ordine Mauriziano

    RECRUITING

    Torino, TO, 10128, Italy

  • AOU Careggi

    RECRUITING

    Florence, 50019, Italy

  • AOU Città della Salute e della Scienza di Torino

    RECRUITING

    Torino, TO, 10126, Italy

  • AOU Maggiore della Carità

    RECRUITING

    Novara, 28100, Italy

  • AOU San Giovanni di Dio e Ruggi d'Aragona

    RECRUITING

    Salerno, SA, 84131, Italy

  • AOU Universitaria Arcispedale Sant'Anna

    RECRUITING

    Ferrara, FE, 44124, Italy

  • ASST Cremona

    RECRUITING

    Cremona, CR, 26100, Italy

  • ASST Grande Ospedale Metropolitano Niguarda

    RECRUITING

    Milan, MI, 20162, Italy

  • ASST Spedali Civili

    RECRUITING

    Brescia, BS, 25123, Italy

  • ASST Valle Olona

    RECRUITING

    Busto Arsizio, VA, 21052, Italy

  • Azienda Ospedale-Università Padova

    NOT_YET_RECRUITING

    Padova, 35100, Italy

  • Azienda Ospedaliera Ospedali Riuniti Villa Sofia - Cervello

    RECRUITING

    Palermo, PA, 90146, Italy

  • Azienda Ospedaliera S. Croce e Carle

    RECRUITING

    Cuneo, CN, 12100, Italy

  • Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli

    RECRUITING

    Naples, 80131, Italy

  • Azienda Ospedaliero Universitaria Delle Marche

    NOT_YET_RECRUITING

    Ancona, 60126, Italy

  • Azienda Ospeldaliera Universitaria Federico II

    NOT_YET_RECRUITING

    Naples, 80131, Italy

  • Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico

    RECRUITING

    Milan, MI, 20122, Italy

  • Fondazione Policlinico Tor Vergata

    RECRUITING

    Roma, RM, 00133, Italy

  • Fundeni Clinical Institute

    RECRUITING

    Bucharest, 022328, Romania

  • IOV Istituto Oncologico Veneto

    RECRUITING

    Castelfranco Veneto, TV, 31033, Italy

  • IRCCS Ospedale Policlinico San Martino

    RECRUITING

    Genova, GE, 16132, Italy

  • IRST Istituto Romagnolo per lo Studio dei Tumori Dino Amadori

    RECRUITING

    Meldola, 47014, Italy

  • Ospedale "A. Perrino"

    RECRUITING

    Brindisi, BR, 72100, Italy

  • Ospedale San Bortolo

    RECRUITING

    Vicenza, 36100, Italy

  • Ospedale Sant'Andrea

    RECRUITING

    Roma, RM, 00189, Italy

  • Ospedale Santa Maria della Misericordia

    RECRUITING

    Perugia, PG, 06156, Italy

  • Ospedale Santa Maria delle Croci

    RECRUITING

    Ravenna, RA, 48121, Italy

  • Ospedale Valduce

    RECRUITING

    Como, CO, 22100, Italy

  • Ospedale infermi di Rimini

    RECRUITING

    Rimini, RN, 47923, Italy

  • Policlinico Sant'Orsola-Malpighi

    RECRUITING

    Bologna, BO, 40138, Italy

  • Policlinico Umberto I

    RECRUITING

    Roma, RM, 00161, Italy

  • Policlinico Universitario Fondazione Agostino Gemelli

    RECRUITING

    Roma, RM, 00168, Italy

  • Presidio Ospedaliero "Santo Spirito"

    NOT_YET_RECRUITING

    Pescara, PE, 65124, Italy

  • The Hospital of Lithuanian University of Health Sciences Kauno Klinikos

    RECRUITING

    Kaunas, 50161, Lithuania

  • University Clinical Center in Gdańsk

    RECRUITING

    Gdansk, 80-214, Poland

  • University Hospital Aachen

    RECRUITING

    Aachen, 52074, Germany

  • University Hospital Greifswald

    RECRUITING

    Greifswald, 17475, Germany

  • University Hospital Halle

    RECRUITING

    Halle, 06120, Germany

  • University Hospital La Fe

    RECRUITING

    Valencia, 46026, Spain

  • University Hospital of Rostock

    RECRUITING

    Rostock, 18507, Germany

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