Cord blood immune cells tested against tough leukemia

NCT ID NCT04347616

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tested a new treatment for adults with acute myeloid leukemia that had come back or not responded to standard therapy. The treatment involved giving patients natural killer cells grown from donated umbilical cord blood, along with a drug called IL-2 to help those cells survive and work. Only 9 people took part before the study was stopped early, so we have limited information on how well it works or its safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

natural killer cells from umbilical cord blood, plus interleukin-2 (IL-2)

What this could lead to

If it works, this could point toward a new treatment option for people with hard-to-treat acute myeloid leukemia who cannot have a stem cell transplant.

What could go wrong

This was a very early, small trial (only 9 people) that was terminated early, so results are limited. The treatment also carries risks like severe side effects or graft-versus-host disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia myelodysplastic syndrome with excess blasts-2 Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Radboud University Medical Center

    Nijmegen, Netherlands