New gene therapy combo shows promise in ovarian cancer trial

NCT ID NCT03393884

Ongoing Disease control Sponsor: Imunon Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a gene therapy called IMNN-001 to standard chemotherapy can help people with advanced ovarian, fallopian tube, or peritoneal cancer live longer without their cancer growing. About 130 newly diagnosed patients will receive either the combination or chemotherapy alone. The goal is to see if the combination is safe and more effective at delaying cancer progression.

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Conditions

The condition(s) this trial relates to.

Carcinoma, Ovarian Epithelial fallopian tube cancer fallopian tube neoplasm ovarian carcinoma primary peritoneal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EPITHELIAL OVARIAN CANCER FALLOPIAN TUBE CANCER PRIMARY PERITONEAL CANCER

Contacts and locations

Locations

Advent Health

Orlando, Florida, 32803, United States
CHUM

Montreal, H2X 0A9, Canada
Chattanooga Women's Health

Chattanooga, Tennessee, 37403, United States
Gynecologic Oncology Associates (Hoag Hospital)

Newport Beach, California, 92663, United States
Hackensack University Medical Center

Hackensack, New Jersey, 07601, United States
Innovative Clinical Research

Whittier, California, 90603, United States
MD Anderson at Cooper

Camden, New Jersey, 08105, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Mitchell Cancer Institute (University of South Alabama)

Mobile, Alabama, 36604, United States
Monter Cancer Center

Lake Success, New York, 11042, United States
NYU Langone

New York, New York, 10016, United States
NYU Langone, Long Island

Mineola, New York, 11501, United States
Providence Cancer Institute

Portland, Oregon, 97213, United States
Providence Health Care

Spokane, Washington, 99204, United States
Sanford Health

Sioux Falls, South Dakota, 57104, United States
Stephenson Cancer Center - Oklahoma University

Oklahoma City, Oklahoma, 73104, United States
The West Clinic

Germantown, Tennessee, 38138, United States
University of Alabama Birmingham

Birmingham, Alabama, 35233, United States
Washington University School of Medicine in St. Louis

St Louis, Missouri, 63110, United States
Women's Care Florida

St. Petersburg, Florida, 33701, United States

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