New combo therapy for HPV throat cancer shows promise in early trial

NCT ID NCT03799445

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 38 times

Summary

This phase 2 study tested a combination of two immunotherapy drugs (ipilimumab and nivolumab) plus radiation therapy in 37 patients with advanced HPV-positive throat cancer. The goal was to see if the treatment was safe and could shrink or eliminate tumors. The study was terminated early, but results help guide future research on using the immune system to fight this cancer.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.