Quick immune boost before breast cancer surgery: does it work?

NCT ID NCT05180006

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving a short course of immunotherapy (atezolizumab, alone or with other drugs) before standard treatment could increase immune cell activity in early-stage breast cancer. It involved 33 patients with triple-negative or HER2-positive breast cancer. The trial was terminated early, so the full results are not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Atezolizumab (with or without bevacizumab, trastuzumab, or pertuzumab)

What this could lead to

If successful, this could show that a short course of immunotherapy before standard treatment helps the immune system fight breast cancer more effectively.

What could go wrong

This was a small, early-phase trial that was terminated, so results are limited. The study focused on immune cell changes, not direct patient outcomes like survival.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm HER2 positive breast carcinoma triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Gustave Roussy

    Villejuif, 94800, France