New drug combo shows promise in saving voice boxes of cancer patients
NCT ID NCT04030455
First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 21 times
Summary
This study tested a treatment that combines two chemotherapy drugs (cisplatin and docetaxel) with an immunotherapy drug (pembrolizumab) in 28 patients with stage II or III laryngeal cancer. The goal was to see if this approach could control the cancer and allow patients to keep their larynx (voice box). After four cycles, 75% of patients had no cancer detectable in tissue samples. The treatment aims to control the disease, not cure it, and patients may need ongoing monitoring or additional therapy.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
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