Tiny study probes how radiation wakes up immune cells in lung tumors

NCT ID NCT03603002

First seen Jun 26, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This pilot study looked at how radiation therapy changes immune cells inside stage I lung cancer tumors. Researchers took biopsies before and after radiation to track T-cell changes and identify tumor antigens. Only 6 people took part, so the goal was to gather early data, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help researchers understand how radiation therapy triggers the immune system against lung cancer, potentially guiding future combination treatments.
What could go wrong
This is a very small pilot study with only 6 participants, so results may not apply broadly. It is designed to gather information, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NON-SMALL CELL LUNG CANCER STAGE I are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bayview Medical Center

    Baltimore, Maryland, 21224, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.