New sealant aims to stop brain fluid leaks during neurosurgery

NCT ID NCT07651826

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a special sealant called Immiseal that is applied during brain or spine surgery to prevent leaks of cerebrospinal fluid. It is used along with standard repair methods to create a watertight seal. The study follows adults aged 18 to 75 who need dural repair after surgery or injury. Researchers will check for infections and fluid leaks for about 100 days after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Immiseal Dural Sealant System
What this could lead to
If successful, this sealant could provide a reliable way to prevent cerebrospinal fluid leaks after brain or spine surgery, reducing complications.
What could go wrong
This is an observational study with a small group of 85 people, so results may not apply to everyone. Risks include infection or the sealant not working as expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Riga East Clinical University Hospital

    RECRUITING

    Riga, Latvia

More trials for these conditions

Other studies related to the condition(s) this trial covers.