New sealant aims to stop brain fluid leaks during neurosurgery

NCT ID NCT07651826

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a special sealant called Immiseal that is applied during brain or spine surgery to prevent leaks of cerebrospinal fluid. It is used along with standard repair methods to create a watertight seal. The study follows adults aged 18 to 75 who need dural repair after surgery or injury. Researchers will check for infections and fluid leaks for about 100 days after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Immiseal Dural Sealant System

What this could lead to

If successful, this sealant could provide a reliable way to prevent cerebrospinal fluid leaks after brain or spine surgery, reducing complications.

What could go wrong

This is an observational study with a small group of 85 people, so results may not apply to everyone. Risks include infection or the sealant not working as expected.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain neoplasm cerebrospinal fluid leak cerebrovascular disorder congenital nervous system disorder Surgical Wound Infection traumatic brain injury vertebral column disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Riga East Clinical University Hospital

    RECRUITING

    Riga, Latvia

    Contact Phone: •••-•••-•••• Email: •••••@•••••