New study probes protein levels to predict drug response in head and neck cancer

NCT ID NCT05816785

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 26 times

Summary

This study looks at whether a protein called AXL in head and neck tumors affects how well a combination of two drugs (imatinib and cetuximab) works. About 15 adults with head and neck cancer will receive these drugs in the short window between diagnosis and their standard treatment (surgery or radiation). The main goal is to measure changes in a cell growth marker (Ki67) in tumor samples taken before and after the drug combination. This is an early-phase trial focused on understanding the biology, not on curing the disease.

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Contacts and locations

Locations

  • University of Wisconsin Carbone Cancer Center

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.