New combo aims to stall Hard-to-Treat gut tumors

NCT ID NCT05152472

First seen Jan 11, 2026 · Last updated May 16, 2026 · Updated 16 times

Summary

This study tests whether adding the immunotherapy drug atezolizumab to the standard drug imatinib can better control advanced gastrointestinal stromal tumors (GIST) that have stopped responding to other treatments. About 110 adults with inoperable or spreading GIST will be randomly assigned to receive either imatinib alone or imatinib plus atezolizumab. The main goal is to see how long the cancer stays under control.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Poitiers

    RECRUITING

    Poitiers, 86000, France

    Contact Email: •••••@•••••

  • Centre Antoine Lacassagne

    RECRUITING

    Nice, 06189, France

    Contact Email: •••••@•••••

  • Centre Eugène Marquis

    RECRUITING

    Rennes, 35042, France

    Contact Email: •••••@•••••

  • Centre Léon Bérard

    RECRUITING

    Lyon, Rhône, 69373, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Oscar Lambret

    RECRUITING

    Lille, 59020, France

    Contact Email: •••••@•••••

  • Centre Paul Strauss

    NOT_YET_RECRUITING

    Strasbourg, 67033, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chru Tours

    RECRUITING

    Tours, 37044, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Robert Debré

    RECRUITING

    Reims, 51090, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital de La Timone

    RECRUITING

    Marseille, 13385, France

    Contact Email: •••••@•••••

  • ICANS CHRU de Strasbourg

    TERMINATED

    Strasbourg, 67200, France

  • Institut Bergonié

    RECRUITING

    Bordeaux, 33076, France

    Contact Email: •••••@•••••

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, 94805, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut de cancérologie de l'Ouest

    RECRUITING

    Saint-Herblain, 44805, France

    Contact Email: •••••@•••••

Conditions

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