Supercharging the Body's own defenses to fight Hard-to-Treat GIST

This trial tests whether a patient's own immune cells, called tumor-infiltrating lymphocytes (TILs), can be grown in a lab and then given back to fight advanced gastrointestinal stromal tumors (GIST). The study includes people whose GIST has spread, come back, or cannot be removed by surgery and has stopped responding to standard treatments. Participants receive chemotherapy to prepare their body, then the lab-grown TILs along with a drug called aldesleukin to boost the immune response.