Brain scans vs tape measures: which TMS targeting works best for depression?
NCT ID NCT07043738
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether using a person's brain scan (MRI) to guide TMS treatment for depression works better than the standard scalp-measurement method. 160 adults with major depression will receive accelerated TMS (10 sessions a day for 5 days) with either MRI or scalp targeting. The goal is to see if the extra cost and complexity of MRI targeting leads to better mood improvement.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transcranial Magnetic Stimulation (TMS)
What this could lead to
If MRI-based targeting works better, it could make TMS more effective for depression, though it's more expensive and complex.
What could go wrong
This is an early-stage comparison study, not a treatment trial. The added benefit of MRI targeting may be small or not worth the extra cost and effort.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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