New Antibody-Drug shows promise for Hard-to-Treat lymphoma

NCT ID NCT05365659

Recruiting now Disease control Sponsor: Iksuda Therapeutics Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 2 times

Summary

This early-stage trial tests a new drug called IKS03 in people with advanced B-cell non-Hodgkin lymphoma that has not responded to other treatments. The drug works like a guided missile, targeting a protein (CD19) on cancer cells to deliver a toxic payload. The study aims to find the safest dose and see if it shrinks tumors. About 140 adults will take part.

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Conditions

The condition(s) this trial relates to.

B-cell neoplasm B-cell non-Hodgkin lymphoma diffuse large B-cell lymphoma follicular lymphoma lymphoma mantle cell lymphoma non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

B CELL LYMPHOMA B-CELL NON-HODGKIN LYMPHOMA DIFFUSE LARGE B-CELL LYMPHOMA FOLLICULAR LYMPHOMA MANTLE CELL LYMPHOMA

Contacts and locations

Locations

Hospital Clinico Universitario de Salamanca
RECRUITING

Salamanca, Spain
Hospital Universitario Quironsalud Madrid
RECRUITING

Madrid, Spain
Institut Catala D'Oncologia
RECRUITING

Badalona, Spain
Istituto Europeo Clinico Humanitas
RECRUITING

Milan, Italy
Istituto Europeo di Oncologia
RECRUITING

Milan, Italy
Istituto Nazionale Oncologico Candiolo
RECRUITING

Candiolo, Italy
Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele
RECRUITING

Milan, Italy
Jewish General Hospital
RECRUITING

Montreal, Quebec, H3T 1E2, Canada
Linear Clinical Research
RECRUITING

Perth, Western Australia, Australia
Royal Adelaide Hospital
RECRUITING

Adelaide, South Australia, Australia
Royal Hobart Hospital
RECRUITING

Hobart, Tasmania, 7000, Australia
University of Maryland Baltimore
WITHDRAWN

Baltimore, Maryland, 21201, United States
Westmead Hospital
RECRUITING

Westmead, New South Wales, 2145, Australia

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