New immune boost for rare immune disorder? small trial underway

NCT ID NCT07076446

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a drug called IgPro20, a type of immune globulin given under the skin, in adults with primary immunodeficiency who have never received such treatment. The goal is to see how the drug moves through the body and whether it is safe. Only 8 participants are enrolled, making this a very early look at the therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IgPro20 (immune globulin subcutaneous, 20% liquid)

What this could lead to

If successful, this could provide a new treatment option for people with primary immunodeficiency who have not previously received immune globulin therapy.

What could go wrong

This is a very small, early-phase study with only 8 participants, so results may not apply to everyone. Side effects like infusion reactions or infections are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

inborn error of immunity Primary Immunodeficiency Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Allergy & Clinical Immunology

    Pittsburgh, Pennsylvania, 15241, United States

  • Allergy, Asthma and Clinical Research Center

    Oklahoma City, Oklahoma, 73120, United States

  • Immunoe Health Centers

    Centennial, Colorado, 80112, United States

  • Johns Hopkins Bayview Medical Center

    Baltimore, Maryland, 21224, United States

  • Medical Research of Arizona

    Scottsdale, Arizona, 85251, United States

  • Midwest Immunology

    Plymouth, Minnesota, 55446, United States

  • Research Solutions of AZ

    Litchfield Park, Arizona, 85340, United States

  • Washington University

    St Louis, Missouri, 63141, United States