Protein test may predict immunotherapy success in advanced melanoma

NCT ID NCT07436390

First seen Feb 28, 2026 · Last updated May 13, 2026 · Updated 15 times

Summary

This study looked at 132 people with advanced melanoma to see if levels of a protein called interferon-gamma (IFN-γ) in tumor tissue and blood could predict how well they would respond to first-line immunotherapy drugs. Researchers also explored whether gut bacteria play a role in treatment outcomes. The goal is to help doctors personalize treatment and avoid giving ineffective therapies to patients who are unlikely to benefit.

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Contacts and locations

Locations

  • Institute of Oncology Ljubljana

    Ljubljana, 1000, Slovenia

Conditions

Explore the condition pages connected to this study.