New hope for Hard-to-Treat stomach cancer: first human trial launches

NCT ID NCT05489237

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 21 times

Summary

This study is the first time IDRX-42 is being tested in people. It is for adults with advanced GIST (a type of stomach or digestive tract cancer) that has spread or cannot be removed by surgery. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. About 278 participants will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

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Locations

  • GSK Investigational Site

    RECRUITING

    Miami, Florida, 33136, United States

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  • GSK Investigational Site

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    Chicago, Illinois, 60611, United States

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    Boston, Massachusetts, 02215, United States

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  • GSK Investigational Site

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    St Louis, Missouri, 63129, United States

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  • GSK Investigational Site

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    New York, New York, 10065, United States

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  • GSK Investigational Site

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    Portland, Oregon, 97239, United States

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  • GSK Investigational Site

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    Philadelphia, Pennsylvania, 19111, United States

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  • GSK Investigational Site

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    Houston, Texas, 77030, United States

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  • GSK Investigational Site

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    Leuven, 3000, Belgium

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  • GSK Investigational Site

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    Beijing, 100142, China

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  • GSK Investigational Site

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    Guangzhou, China

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  • GSK Investigational Site

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    Wuhan, 430022, China

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  • GSK Investigational Site

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    Bordeaux, 33076, France

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  • GSK Investigational Site

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    Lyon, France

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  • GSK Investigational Site

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    Marseille, 13005, France

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  • GSK Investigational Site

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    Villejuif, 94805, France

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  • GSK Investigational Site

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    Berlin, Germany

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  • GSK Investigational Site

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    Essen, 45122, Germany

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  • GSK Investigational Site

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    Milan, 20133, Italy

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  • GSK Investigational Site

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    Chiba, 277-8577, Japan

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  • GSK Investigational Site

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    Tokyo, 104-0045, Japan

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  • GSK Investigational Site

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    Amsterdam, 1066 CX, Netherlands

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  • GSK Investigational Site

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    Rotterdam, 3075 EA, Netherlands

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  • GSK Investigational Site

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    Seongnam-si Gyeonggi-do, 463-707, South Korea

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  • GSK Investigational Site

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    Seoul, 120-752, South Korea

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  • GSK Investigational Site

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    Seoul, 3080, South Korea

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  • GSK Investigational Site

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    Seoul, 5505, South Korea

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  • GSK Investigational Site

    RECRUITING

    Seoul, 6351, South Korea

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  • GSK Investigational Site

    RECRUITING

    Barcelona, Spain

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  • GSK Investigational Site

    RECRUITING

    Leeds, LS9 7TF, United Kingdom

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  • GSK Investigational Site

    RECRUITING

    London, SW3 6JJ, United Kingdom

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Conditions

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