Liver cancer trial tests new chemo combo without embolization

NCT ID NCT03727633

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This phase 2 trial tested a liver-directed chemotherapy using idarubicin mixed with lipiodol (a fatty contrast agent) injected directly into the liver artery. The goal was to see if this could control non-spreading liver cancer in 44 patients with cirrhosis. The study was terminated early, so results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

idarubicin and lipiodol

What this could lead to

If it works, this could offer a new way to control liver cancer in patients who cannot have surgery or other standard treatments.

What could go wrong

This is an early phase 2 trial with only 44 participants, and it was terminated early. The treatment may not control the disease or could cause side effects like liver damage or low blood counts.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU d'Angers

    Angers, 49933, France

  • CHU de Dijon

    Dijon, 21079, France

  • CHU de Montpellier

    Montpellier, 34295, France

  • CHU de Nice

    Nice, 06202, France