Could weekly IV line changes cut ICU workload without raising infection risk?

NCT ID NCT07183592

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares changing IV tubing every 7 days versus every 4 days in ICU patients with central venous catheters. The goal is to see if the longer interval increases infection rates. About 2,830 adults will take part. If 7-day changes are safe, it could save nursing time and reduce medical waste.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Infusion set replacement procedure

What this could lead to

If successful, this could show that changing IV tubing every 7 days is as safe as every 4 days, potentially reducing nurse workload and hospital costs without raising infection risk.

What could go wrong

This is a large but early-stage trial. The 7-day schedule might still lead to more infections, and results may not apply to all ICU patients or settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

nosocomial infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AP-HP - Henri Mondor Hospital

    NOT_YET_RECRUITING

    Créteil, 94000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • AP-HP - Saint Louis

    NOT_YET_RECRUITING

    Paris, 75475, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • AP-HP - Tenon Hospital

    NOT_YET_RECRUITING

    Paris, 75020, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Albi Hospital

    NOT_YET_RECRUITING

    Albi, 81000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Angers University Hospital

    RECRUITING

    Angers, 49933, France

    Contact Phone: •••-•••-••••

  • Belfort Hospital

    NOT_YET_RECRUITING

    Belfort, 90015, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bourges Hospital

    NOT_YET_RECRUITING

    Bourges, 18000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH Carcassonne

    NOT_YET_RECRUITING

    Carcassonne, 11000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH Le Mans

    NOT_YET_RECRUITING

    Le Mans, 72000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH Saint-Nazaire

    NOT_YET_RECRUITING

    Saint-Nazaire, 44606, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Rennes - service MIR

    NOT_YET_RECRUITING

    Rennes, 35033, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Rennes - service Réa chir

    NOT_YET_RECRUITING

    Rennes, 35033, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Tours

    NOT_YET_RECRUITING

    Tours, 37000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Caen University Hospital

    NOT_YET_RECRUITING

    Caen, 14033, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chartres Hospital

    NOT_YET_RECRUITING

    Chartres, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cholet Hospital

    NOT_YET_RECRUITING

    Cholet, 49300, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Colombes Hospital

    NOT_YET_RECRUITING

    Colombes, 92700, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Corbeil-Essonnes Hospital

    NOT_YET_RECRUITING

    Corbeil-Essonnes, 91106, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dijon University Hospital

    NOT_YET_RECRUITING

    Dijon, 21079, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Garches Hospital

    NOT_YET_RECRUITING

    Garches, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • La Réunion University Hospital

    NOT_YET_RECRUITING

    Saint-Pierre, La Réunion, BP350 97448, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Le Puy en Velay Hospital

    NOT_YET_RECRUITING

    Le Puy-en-Velay, 43000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Macon Hospital

    NOT_YET_RECRUITING

    Mâcon, 71000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nantes University Hospital

    NOT_YET_RECRUITING

    Nantes, 44093, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Orleans University Hospital

    NOT_YET_RECRUITING

    Orléans, 45067, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pontoise Hospital

    NOT_YET_RECRUITING

    Pontoise, 95300, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Strasbourg University Hospital

    NOT_YET_RECRUITING

    Strasbourg, 67091, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••