Could weekly IV line changes cut ICU workload without raising infection risk?

NCT ID NCT07183592

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares changing IV tubing every 7 days versus every 4 days in ICU patients with central venous catheters. The goal is to see if the longer interval increases infection rates. About 2,830 adults will take part. If 7-day changes are safe, it could save nursing time and reduce medical waste.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Infusion set replacement procedure
What this could lead to
If successful, this could show that changing IV tubing every 7 days is as safe as every 4 days, potentially reducing nurse workload and hospital costs without raising infection risk.
What could go wrong
This is a large but early-stage trial. The 7-day schedule might still lead to more infections, and results may not apply to all ICU patients or settings.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AP-HP - Henri Mondor Hospital

    NOT_YET_RECRUITING

    Créteil, 94000, France

  • AP-HP - Saint Louis

    NOT_YET_RECRUITING

    Paris, 75475, France

  • AP-HP - Tenon Hospital

    NOT_YET_RECRUITING

    Paris, 75020, France

  • Albi Hospital

    NOT_YET_RECRUITING

    Albi, 81000, France

  • Angers University Hospital

    RECRUITING

    Angers, 49933, France

  • Belfort Hospital

    NOT_YET_RECRUITING

    Belfort, 90015, France

  • Bourges Hospital

    NOT_YET_RECRUITING

    Bourges, 18000, France

  • CH Carcassonne

    NOT_YET_RECRUITING

    Carcassonne, 11000, France

  • CH Le Mans

    NOT_YET_RECRUITING

    Le Mans, 72000, France

  • CH Saint-Nazaire

    NOT_YET_RECRUITING

    Saint-Nazaire, 44606, France

  • CHU Rennes - service MIR

    NOT_YET_RECRUITING

    Rennes, 35033, France

  • CHU Rennes - service Réa chir

    NOT_YET_RECRUITING

    Rennes, 35033, France

  • CHU Tours

    NOT_YET_RECRUITING

    Tours, 37000, France

  • Caen University Hospital

    NOT_YET_RECRUITING

    Caen, 14033, France

  • Chartres Hospital

    NOT_YET_RECRUITING

    Chartres, France

  • Cholet Hospital

    NOT_YET_RECRUITING

    Cholet, 49300, France

  • Colombes Hospital

    NOT_YET_RECRUITING

    Colombes, 92700, France

  • Corbeil-Essonnes Hospital

    NOT_YET_RECRUITING

    Corbeil-Essonnes, 91106, France

  • Dijon University Hospital

    NOT_YET_RECRUITING

    Dijon, 21079, France

  • Garches Hospital

    NOT_YET_RECRUITING

    Garches, France

  • La Réunion University Hospital

    NOT_YET_RECRUITING

    Saint-Pierre, La Réunion, BP350 97448, France

  • Le Puy en Velay Hospital

    NOT_YET_RECRUITING

    Le Puy-en-Velay, 43000, France

  • Macon Hospital

    NOT_YET_RECRUITING

    Mâcon, 71000, France

  • Nantes University Hospital

    NOT_YET_RECRUITING

    Nantes, 44093, France

  • Orleans University Hospital

    NOT_YET_RECRUITING

    Orléans, 45067, France

  • Pontoise Hospital

    NOT_YET_RECRUITING

    Pontoise, 95300, France

  • Strasbourg University Hospital

    NOT_YET_RECRUITING

    Strasbourg, 67091, France

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