Engineered immune cells aim to tame stubborn IBD

NCT ID NCT07544160

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests a new treatment called ICG318 CAR-T for people with inflammatory bowel disease (IBD) that hasn't improved with standard therapies. The treatment uses a patient's own immune cells, modified in a lab to target and calm the overactive immune response causing IBD. The main goal is to check safety, but researchers also hope to see if patients can achieve long-term remission without needing other medications.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Zhongshan people's hospital

    Zhongshan, Guangdong, 528403, China

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Other studies related to the condition(s) this trial covers.