Common pain pill put to the test: is ibuprofen safe after major surgery?

NCT ID NCT05575700

Summary

This large study tested whether taking ibuprofen for eight days after hip or knee replacement surgery is safe. Nearly 3,000 patients were randomly given either ibuprofen or a placebo pill to see which group had fewer serious complications. The goal was to find the best balance between effective pain relief and avoiding risks like heart problems, kidney issues, or stomach bleeding.

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Contacts and locations

Locations

  • Aalborg University Hospital

    Farsø, 9640, Denmark

  • Bispebjerg Hospital

    Copenhagen NV, 2400, Denmark

  • Gentofte Hospital

    Hellerup, 2900, Denmark

  • Nordsjællands Hospital Hillerød

    Hillerød, 3400, Denmark

  • Næstved Hospital

    Næstved, 4700, Denmark

  • Odense University Hospital

    Odense, 3900, Denmark

  • Private Hospital Gildhøj

    Brøndby, 2605, Denmark

  • Silkeborg Regional Hospital

    Silkeborg, 8600, Denmark

  • Svendborg Hospital

    Svendborg, 5700, Denmark

  • Vejle Sygehus

    Vejle, 7100, Denmark

  • Zealand University Hospital

    Køge, 4600, Denmark

Conditions

Explore the condition pages connected to this study.