Study aims to cut opioid use after wisdom tooth surgery
NCT ID NCT06539741
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at why some people need extra opioids for pain after having their wisdom teeth removed, while others get enough relief from ibuprofen alone. Researchers will study 200 adults having at least one impacted wisdom tooth pulled. They hope to find clues in genes or blood markers that could help doctors prescribe fewer unnecessary opioids in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ibuprofen
- What this could lead to
- If successful, this could help doctors prescribe fewer opioids after dental surgery by identifying who will get enough pain relief from ibuprofen alone.
- What could go wrong
- This is an early observational study, not testing a new treatment. It may not lead to changes in prescribing practices.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Pennsylvania School of Dental Medicine
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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