ALS patients get early access to potential slowing drug

NCT ID NCT06743776

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This program offers the drug ibudilast (MN-166) to people with ALS who cannot join other clinical trials. Participants take the drug by mouth, starting at a lower dose and increasing. The goal is to see if ibudilast can slow the progression of ALS. The program also collects blood samples to study biomarkers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ibudilast (MN-166)

What this could lead to

If it works, this could help slow the progression of ALS in patients who cannot join other clinical trials.

What could go wrong

This is an expanded access program, not a formal trial, so results are less certain. Ibudilast may not slow ALS for everyone and could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Augusta University

    AVAILABLE

    Augusta, Georgia, 30912, United States

    Contact

    Contact Email: •••••@•••••

  • Duke University

    AVAILABLE

    Durham, North Carolina, 27705, United States

    Contact Email: •••••@•••••

    Contact

  • Hennepin Healthcare Research Institute

    AVAILABLE

    Minneapolis, Minnesota, 55415, United States

    Contact Email: •••••@•••••

    Contact

  • Hospital for Special Care

    AVAILABLE

    New Britain, Connecticut, 06053, United States

    Contact Email: •••••@•••••

    Contact

  • Indiana University - IU Health Neuroscience Center

    AVAILABLE

    Indianapolis, Indiana, 46202, United States

    Contact

    Contact Email: •••••@•••••

  • Lehigh Valley Health Network

    AVAILABLE

    Allentown, Pennsylvania, 18103, United States

    Contact

    Contact Email: •••••@•••••

  • Mayo Clinic

    AVAILABLE

    Scottsdale, Arizona, 85259, United States

    Contact Email: •••••@•••••

    Contact

  • Mayo Clinic

    AVAILABLE

    Jacksonville, Florida, 32224, United States

    Contact

    Contact Email: •••••@•••••

  • Mayo Clinic

    AVAILABLE

    Rochester, Minnesota, 55905, United States

    Contact Email: •••••@•••••

    Contact

  • Nova Southeastern University

    AVAILABLE

    Davie, Florida, 33314, United States

    Contact Email: •••••@•••••

    Contact

  • SUNY Upstate Medical University

    AVAILABLE

    Syracuse, New York, 13210, United States

    Contact

    Contact Email: •••••@•••••

  • Semmes Murphey Foundation

    AVAILABLE

    Memphis, Tennessee, 38120, United States

    Contact

    Contact Email: •••••@•••••

  • UCI Health

    AVAILABLE

    Orange, California, 92868, United States

    Contact

    Contact Email: •••••@•••••

  • University of California, San Francisco

    AVAILABLE

    San Francisco, California, 94143, United States

    Contact

    Contact Email: •••••@•••••

  • University of Virginia

    AVAILABLE

    Charlottesville, Virginia, 22908, United States

    Contact Email: •••••@•••••

    Contact