Promising drug cocktail takes on deadly brain cancer

NCT ID NCT03535350

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This early-phase trial tests whether adding the drug ibrutinib to standard radiation and chemotherapy is safe for people with a newly diagnosed aggressive brain cancer called glioblastoma. The study includes 36 participants and looks at different doses based on a specific genetic marker (MGMT). The main goal is to find the highest safe dose and monitor side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center

    Cleveland, Ohio, 44195, United States

Conditions

Explore the condition pages connected to this study.