New hope for tough melanoma: drug targets Cancer's growth signals
NCT ID NCT02581930
First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 29 times
Summary
This study tests a drug called ibrutinib in people with stage IV melanoma (skin cancer that has spread) that did not get better with other treatments. Ibrutinib works by blocking certain enzymes that cancer cells need to grow. The main goal is to see if the drug can shrink tumors, and researchers will also look at how long patients live without the cancer getting worse. About 18 adults will take part.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Los Angeles General Medical Center
Los Angeles, California, 90033, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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UCHealth University of Colorado Hospital
Aurora, Colorado, 80045, United States
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
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University of Kentucky/Markey Cancer Center
Lexington, Kentucky, 40536, United States
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University of Virginia Cancer Center
Charlottesville, Virginia, 22908, United States
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University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin, 53792, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.