New hope for tough lymphoma: targeted drug shows promise

NCT ID NCT01849263

Ongoing Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called ibrutinib in 41 people with follicular lymphoma that returned or didn't respond to prior treatment. Ibrutinib works by blocking certain enzymes that cancer cells need to grow. The main goal was to see how many patients had their tumors shrink or disappear. This is not a cure, but it may help control the disease.

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Conditions

The condition(s) this trial relates to.

follicular lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GRADE 3A FOLLICULAR LYMPHOMA RECURRENT GRADE 1 FOLLICULAR LYMPHOMA RECURRENT GRADE 2 FOLLICULAR LYMPHOMA RECURRENT GRADE 3 FOLLICULAR LYMPHOMA REFRACTORY FOLLICULAR LYMPHOMA

Contacts and locations

Locations

Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States
Juravinski Cancer Centre at Hamilton Health Sciences

Hamilton, Ontario, L8V 5C2, Canada
Kingston Health Sciences Centre

Kingston, Ontario, K7L 2V7, Canada
Mayo Clinic in Arizona

Scottsdale, Arizona, 85259, United States
Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
Metro Minnesota Community Oncology Research Consortium

Saint Louis Park, Minnesota, 55416, United States
National Cancer Centre Singapore

Singapore, 168583, Singapore
National University Hospital Singapore

Singapore, 119074, Singapore
Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416, United States
University Health Network-Princess Margaret Hospital

Toronto, Ontario, M5G 2M9, Canada
University of Wisconsin Carbone Cancer Center - University Hospital

Madison, Wisconsin, 53792, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States

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