New combo therapy aims to stop brain cancer growth in older patients
NCT ID NCT05998642
First seen Nov 18, 2025 · Last updated Jun 14, 2026 · Updated 25 times
Summary
This study tests whether adding the drug ibrutinib to standard chemotherapy can better control primary central nervous system lymphoma (PCNSL) in people who are not eligible for a stem cell transplant. About 30 adults aged 65 or older or with other health issues will receive the combination therapy. The main goal is to see if the cancer stays under control for at least one year.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Allan Blair Cancer Centre
RECRUITINGRegina, Saskatchewan, S4T 7T1, Canada
Contact Phone: •••-•••-••••
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Arthur J.E. Child Comprehensive Cancer Centre
RECRUITINGCalgary, Alberta, T2N 5G2, Canada
Contact Phone: •••-•••-••••
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BCCA - Vancouver
RECRUITINGVancouver, British Columbia, V5Z 4E6, Canada
Contact Phone: •••-•••-••••
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CHU de Quebec-Hopital l'Enfant-Jesus (HEJ)
RECRUITINGQuébec, Quebec, G1J 1Z4, Canada
Contact
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Juravinski Cancer Centre at Hamilton Health Sciences
RECRUITINGHamilton, Ontario, L8V 5C2, Canada
Contact Phone: •••-•••-••••
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Ottawa Hospital Research Institute
RECRUITINGOttawa, Ontario, K1H 8L6, Canada
Contact
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The Research Institute of the McGill University
RECRUITINGMontreal, Quebec, H4A 3J1, Canada
Contact Phone: •••-•••-••••
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University Health Network
RECRUITINGToronto, Ontario, M5G 2M9, Canada
Contact Phone: •••-•••-••••
Conditions
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