New drug combo aims to stop brain cancer from spreading

NCT ID NCT05998642

First seen Nov 18, 2025 · Last updated Apr 30, 2026 · Updated 16 times

Summary

This study tests whether adding the drug ibrutinib to standard chemotherapy can stop primary central nervous system lymphoma from growing or spreading. It is for 30 adults aged 18 or older who are newly diagnosed and cannot have a stem cell transplant due to age or health issues. Researchers will compare the one-year cancer control rate and side effects to usual care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Allan Blair Cancer Centre

    RECRUITING

    Regina, Saskatchewan, S4T 7T1, Canada

    Contact Phone: •••-•••-••••

  • Arthur J.E. Child Comprehensive Cancer Centre

    RECRUITING

    Calgary, Alberta, T2N 5G2, Canada

    Contact Phone: •••-•••-••••

  • BCCA - Vancouver

    RECRUITING

    Vancouver, British Columbia, V5Z 4E6, Canada

    Contact Phone: •••-•••-••••

  • CHU de Quebec-Hopital l'Enfant-Jesus (HEJ)

    RECRUITING

    Québec, Quebec, G1J 1Z4, Canada

    Contact

  • Juravinski Cancer Centre at Hamilton Health Sciences

    RECRUITING

    Hamilton, Ontario, L8V 5C2, Canada

    Contact Phone: •••-•••-••••

  • Ottawa Hospital Research Institute

    RECRUITING

    Ottawa, Ontario, K1H 8L6, Canada

    Contact

  • The Research Institute of the McGill University

    RECRUITING

    Montreal, Quebec, H4A 3J1, Canada

    Contact Phone: •••-•••-••••

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.