New shot could tame high cholesterol without statins

NCT ID NCT07473960

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This Phase 3 trial tests a new injectable drug called IBI306 in 198 Chinese adults with non-familial high cholesterol and mixed high lipids. Participants receive either IBI306 or a placebo every 2 or 4 weeks for 12 weeks. The main goal is to see how much the drug lowers LDL (bad) cholesterol compared to placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
IBI306 (a drug given as an injection every 2 or 4 weeks)
What this could lead to
If successful, this could provide a new treatment option to lower bad cholesterol and reduce heart disease risk for people with high cholesterol.
What could go wrong
This is a relatively small, early-stage Phase 3 trial in Chinese participants only, so results may not apply to other populations. The drug may not lower cholesterol enough or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Peking University Third Hospital

    Beijing, Beijing Municipality, 100083, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.