New shot could tame high cholesterol without statins

NCT ID NCT07473960

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 3 trial tests a new injectable drug called IBI306 in 198 Chinese adults with non-familial high cholesterol and mixed high lipids. Participants receive either IBI306 or a placebo every 2 or 4 weeks for 12 weeks. The main goal is to see how much the drug lowers LDL (bad) cholesterol compared to placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IBI306 (a drug given as an injection every 2 or 4 weeks)

What this could lead to

If successful, this could provide a new treatment option to lower bad cholesterol and reduce heart disease risk for people with high cholesterol.

What could go wrong

This is a relatively small, early-stage Phase 3 trial in Chinese participants only, so results may not apply to other populations. The drug may not lower cholesterol enough or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hyperlipidemia hyperlipidemia, familial combined, LPL related Hyperlipoproteinemia Type II

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University Third Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100083, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••