New shot could tame stubborn high cholesterol

NCT ID NCT07421297

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tests a new injectable drug called SYH2053 in 760 adults with high cholesterol or mixed lipid disorders. Participants receive either the drug or a placebo to see if it safely lowers LDL ('bad') cholesterol. The study aims to offer a new treatment option for people who haven't met their cholesterol goals.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SYH2053 injection

What this could lead to

If it works, this could provide a new injectable option to help control high cholesterol and reduce heart disease risk.

What could go wrong

This is a Phase 3 trial, but results may not show a meaningful benefit over existing treatments. Side effects or lack of long-term safety data could limit its use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hyperlipidemia Hyperlipoproteinemia Type II

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliation: Peking University Third Hospital

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, China

  • Affiliation: Peking University Third Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••