New shot could help lower stubborn high cholesterol
NCT ID NCT07421284
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial tests an injection called SYH2053 for people with high cholesterol that isn't controlled by standard pills. About 900 adults aged 18-75 will receive either the drug or a placebo, on top of their usual cholesterol medication. The main goal is to see if SYH2053 safely lowers bad cholesterol (LDL-C) levels over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SYH2053 injection
- What this could lead to
- If it works, this could provide a new injectable option to help lower bad cholesterol in people who still have high levels despite standard treatments.
- What could go wrong
- This is a Phase 3 trial, but it hasn't started yet. The drug may not lower cholesterol enough or could cause side effects. Results may not apply to everyone with high cholesterol.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Affiliation: Peking University Third Hospital
Beijing, Beijing Municipality, China
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