Hidden danger: flu patients in ICU face fungal lung threat

NCT ID NCT04530799

Completed Knowledge-focused Sponsor: Radboud University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tracked 241 ICU patients with severe influenza to see how many developed a fungal lung infection called IAPA. Researchers collected blood and fluid samples to identify risk factors. The goal is to help doctors spot high-risk patients earlier.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors identify which flu patients in the ICU are most at risk for a serious fungal infection, leading to earlier detection and better care.
What could go wrong: This is an observational study, not a treatment trial. It only looks for patterns and cannot prove cause and effect. Results may not apply to all patients or hospitals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aspergillosis fungal lung infectious disease influenza Invasive Pulmonary Aspergillosis pulmonary aspergilloma respiratory tract infectious disorder viral infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFLUENZA WITH PNEUMONIA PULMONARY ASPERGILLOSIS

Contacts and locations

Locations

AZ Delta

Roeselare, Belgium
AZ St-Jan

Bruges, Belgium
Amiens-Picardie University Hospital

Amiens, 80054, France
AmsterdamUMC, locatie VUmc

Amsterdam, 1081, Netherlands
Centre Hospitalier REgional Universitaire de Lille

Lille, France
Henri Mondor Hopital

Paris, France
Hopital Bichat

Paris, France
Hopital Lariboisiere

Paris, France
Hopital Pontchaillou, Centre Hospitalier Universitaire de Rennes

Rennes, France
Radboudumc

Nijmegen, Gelderland, 6525GA, Netherlands
UZ Leuven

Leuven, Belgium
Universitair Medisch Centrum Groningen

Groningen, Provincie Groningen, 9713, Netherlands

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