Biopsy-Guided drug tweak may extend kidney transplants

NCT ID NCT02444429

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 20 times

Summary

This study tested a strategy using a routine kidney biopsy three months after transplant to guide anti-rejection medication. 346 kidney transplant patients were split into two groups: those with mild inflammation received extra treatment, while those without inflammation had their steroids reduced. The goal was to see if this personalized approach could improve long-term kidney health without increasing side effects.

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Contacts and locations

Locations

  • Département de Néphrologie et Transplantation d'Organes - Hôpital Rangueil - CHU de Toulouse

    Toulouse, 31059, France

  • Institut de Transplantation, Urologie et Néphrologie (ITUN) - CHU de Nantes

    Nantes, 44093, France

  • Service de Néphrologie - Hôpital Claude Huriez - CHU de Lille

    Lille, 59037, France

  • Service de Néphrologie et Transplantation - Nouvel Hôpital Civil - CHRU Strasbourg

    Strasbourg, 67091, France

  • Service de Néphrologie, Hémodialyse, Transplantations Rénales - Hôpital de la Cavale Blanche - CHU de Brest

    Brest, 29609, France

  • Service de Néphrologie, Transplantation et Immunologie Clinique - Hôpital Edouard Herriot - Hospices Civils de Lyon

    Lyon, 69437, France

  • Service de Néphrologie,Transplantation, Dialyse I - Hôpital Pellegrin - CHU Bordeaux

    Bordeaux, 33000, France

  • Service de Transplantation - Hôpital Universitaire Necker

    Paris, 75015, France

Conditions

Explore the condition pages connected to this study.