Can saltwater breathing ease a tough lung infection?
NCT ID NCT07647575
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether inhaling a salty mist (3% hypertonic saline) can improve breathing symptoms in people with nontuberculous mycobacterial (NTM) lung disease who haven't yet started antibiotics. About 262 adults will either start the saltwater treatment right away for 6 months or begin with normal saline for 3 months then switch. The main goal is to see if symptoms like cough and shortness of breath improve more with the stronger salt solution.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 3% hypertonic saline
- What this could lead to
- If it works, this could offer a simple, drug-free way to ease respiratory symptoms and improve mucus clearance in NTM lung disease.
- What could go wrong
- This is an early-stage trial with no phase designation, and the primary endpoint is symptom scores at just 3 months. The effect may be modest or not clinically meaningful.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Taipei Veterans General Hospital
RECRUITINGTaipei, 11217, Taiwan
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