Blood pressure pill showdown pulled before it began

NCT ID NCT02483936

First seen Dec 12, 2025

Summary

This study aimed to compare two different combination pills for controlling high blood pressure: one with olmesartan and chlorthalidone, and another with olmesartan and hydrochlorothiazide (Benicar HCT). The trial was planned for people with uncontrolled hypertension but was withdrawn before any participants were enrolled. No results are available.

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What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

olmesartan medoxomil + chlorthalidone

What this could lead to

If successful, this could offer a new fixed-dose combination pill for controlling high blood pressure.

What could go wrong

The trial was withdrawn before enrolling any participants, so no results are available. It is unclear if the combination would have been safer or more effective than existing options.

Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.